Bulk movement

Bulk movement

In cell biology, bulk flow is the process by which proteins without a sorting signal travel to and from different cellular compartments. Proteins often have sorting signals, either transport signals or retention signals, specifying if a protein will translocate to another compartment within the cell or is retained in the current, membrane-bound, compartment in which it is already located respectively. For instance, proteins with the KDEL sorting signal are specified to return to the endoplasmic reticulum from the Golgi (see vesicular transport). However, proteins lacking a sorting signal will increase in concentration in a specific compartment until it reaches bulk concentration in the donor compartment. At this point, it enters budding vesicles and is transported to an acceptor compartment. It is thus this process which is termed bulk flow.

It is thought that cargo travels through the Golgi cisternae (from cis- to trans- Golgi) via bulk flow.

References

1. Rothman J.E. and Weiland F.T. Protein sorting by transport vesicles. Science 272. 227-234. 1996.

ee also

* Protein targeting
* Vesicle
* COPI
* COPII


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • movement control team — Movement control teams (MCTs) are Army units that decentralize the execution of movement responsibilities on an area basis or at key transportation nodes. The mission of the MCTs is movement control of personnel and materiel as well as the… …   Military dictionary

  • Movement for the Left — Movimento per la Sinistra Leader Nichi Vendola Founded 25 January 2009 …   Wikipedia

  • Bulk carrier — The Sabrina I is a modern Handymax bulk carrier. Class overview Name: Freighter Subclasses …   Wikipedia

  • Movement for Democratic Change (prior to 2005) — {Refimprove|date=July 2009}} Movement for Democratic Change Leader Morgan Tsvangirai …   Wikipedia

  • Movement for Democratic Change (pre-2004) — Infobox Canada Political Party party name = Movement for Democratic Change party wikicolourid = Liberal status = defunct class = fed foundation = 31 September, 1999 dissolution = March 2006 party president = Morgan Tsvangirai leader = Gibson… …   Wikipedia

  • mass movement — an organized effort by a large number of people, esp. those not forming part of the elite of a given society, to bring about pervasive changes in existing social, economic, or political institutions, frequently characterized by charismatic… …   Universalium

  • Break bulk cargo — In shipping, break bulk cargo or general cargo is a term that covers a great variety of goods that must be loaded individually, and not in shipping containers nor in bulk as with oil or grain. Ships that carry this sort of cargo are often called… …   Wikipedia

  • History of the Latter Day Saint movement — For a listing of denominations within the Latter Day Saint movement, see List of denominations in the Latter Day Saint movement. For a history of the largest of these denominations, see History of The Church of Jesus Christ of Latter day Saints.… …   Wikipedia

  • Intelligent design movement — Part of a series of articles on Intelligent design …   Wikipedia

  • Revolutionary Nationalist Movement — For the Honduran political party, see Revolutionary Nationalist Movement (Honduras). Movimiento Nacionalista Revolucionario Founded June 7, 1942 Headquarters La Paz, Bo …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”