Slow reacting substance of anaphylaxis
- Slow reacting substance of anaphylaxis
The Slow reacting substance of anaphylaxis or SRS-A is a mixture of the leukotrienes LTC4, LTD4 and LTE4. Mast cells secrete it during the anaphylactic reaction, inducing inflammation. [cite web|title= Dorland's Medical Dictionary| url= http://www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_s_27zPzhtm | accessdate= December 15|accessyear=2006] It can be found in basophils.
It induced prolonged, slow contraction of smooth muscle and has a major bronchoconstrictor role in asthma. [ cite web| url= http://www.nature.com/nature/journal/v285/n5760/abs/285104a0.html | title = Structure of slow-reacting substance of anaphylaxis from guinea-pig lung |author = Howard R. Morris, Graham W. Taylor, Priscilla J. Piper, John R. Tippins| accessdate= December 15|accessyear=2006]
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slow-reacting substance of anaphylaxis — n a mixture of three leukotrienes produced in anaphylaxis that causes contraction of smooth muscle after minutes in contrast to histamine which acts in seconds and that is prob. responsible for the bronchoconstriction occurring in anaphylaxis… … Medical dictionary
slow-reacting substance — n SLOW REACTING SUBSTANCE OF ANAPHYLAXIS abbr. SRS … Medical dictionary
slow reacting substance of anaphylaxis — (= SRS A) Potent bronchoconstrictor and inflammatory agent released by mast cells; an important mediator of allergic bronchial asthma. A mixture of three leukotrienes (LTC4 mainly, LTD4 and LTE4) … Dictionary of molecular biology
anaphylaxis — n. 1. [Gr. ana back, way from + fy laxis security, protection.] 1. (Med.) hypersensitivity (to a protein or drug) resulting from prior contact with a substance. [WordNet 1.5] 2. (Med.) an immediate but transient allergic reaction to an antigenic… … The Collaborative International Dictionary of English
substance — Stuff; material. SYN: substantia [TA], matter. [L. substantia, essence, material, fr. sub sto, to stand under, be present] alpha s. SYN: reticular s. (1). anterior perforated s. [TA] a region at the base … Medical dictionary
anaphylaxis — An induced systemic or generalized sensitivity; at times the term a. is used for anaphylactic shock. The term is commonly used to denote the immediate, transient kind of immunologic (allergic) reaction characterized by contraction of smooth … Medical dictionary
SRSA — slow reacting substance of anaphylaxis … Medical dictionary
SRSA — • slow reacting substance of anaphylaxis … Dictionary of medical acronyms & abbreviations
SRS-A — • slow reacting substance of anaphylaxis … Dictionary of medical acronyms & abbreviations
SRS-A — Slow reacting substance of anaphylaxis (Sustancia de reacción lenta de la anafilaxia) … Diccionario de siglas médicas y otras abreviaturas
