- Hydrotrope
A hydrotrope is a compound that solubilises
hydrophobic compounds in aqueous solutions. Typically, hydrotropes consist of ahydrophilic part and ahydrophobic part (likesurfactants ) but the hydrophobic part is generally too small to cause spontaneous self-aggregation.
Hydrotropes do not have acritical concentration above whichself-aggregation 'suddenly' starts to occur (as found formicelle - andvesicle -forming surfactants, which have acritical micelle concentration or cmc and acritical vesicle concentration or cvc, respectively). Instead, some hydrotropes aggregate in a step-wise self-aggregation process, gradually increasing aggregation size. However, many hydrotropes do not seem to self-aggregate at all, unless asolubilisate has been added. Hydrotropes are in use industrially. Hydrotropes are used in detergent formulations to allow more concentrated formulations of surfactants. Examples of hydrotropes includesodium p-toluenesulfonate andsodium xylene sulfonate .
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