Tetrahydrozoline

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ImageFile=Tetrahydrozoline.svg
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IUPACName=2-(1-tetralinyl)-4,5-dihydro-1H-imidazole
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PubChem=5419
SMILES=C1CC(C2=CC=CC=C2C1)C3=NCCN3
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Formula=C₁₃H₁₆N₂
MolarMass=200.27954
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Tetrahydrozoline is a derivative of imidazoline, which is found in over-the-counter eye drops and nasal sprays. Other derivatives include naphazoline, oxymetazoline, and xylometazoline. Poisoning can result from an overdose.

Tetrahydrozoline is widely believed to cause violent diarrhea if administered orally, as in a few drops of Visine in an unsuspecting person's beverage. However, this is an urban legend, and the actual results may vary from severe nausea and vomiting to seizures or a coma. See Visine Prank. [ [http://www.snopes.com/medical/myths/visine.asp Urban Legends Reference Pages: Visine Prank ] ] Diarrhea is "not" a side effect.

Tetrahydrozoline is an alpha agonistcite journal |author=Dahlström M, Lindgren F, Berntsson K, "et al" |title=Evidence for different pharmacological targets for imidazoline compounds inhibiting settlement of the barnacle Balanus improvisus |journal=J. Exp. Zoolog. Part A Comp. Exp. Biol. |volume=303 |issue=7 |pages=551–62 |year=2005 |month=July |pmid=15945078 |doi=10.1002/jez.a.163 |url=http://dx.doi.org/10.1002/jez.a.163] and its main mechanism of action is the constriction of conjunctival blood vessels. This serves to relieve the redness of the eye caused by minor ocular irritants.

ee also

*Visine

References