A Kinetoplast is a disk-shaped mass of circular
DNAs inside a large mitochondrionthat contains many copies of the mitochondrial genome. [cite journal |author=Shapiro TA, Englund PT |title=The structure and replication of kinetoplast DNA |journal=Annu. Rev. Microbiol. |volume=49 |pages=117–43 |year=1995 |pmid=8561456 |doi=10.1146/annurev.mi.49.100195.001001] [cite journal |author=Shlomai J |title=The structure and replication of kinetoplast DNA |journal=Curr. Mol. Med. |volume=4 |issue=6 |pages=623–47 |year=2004 |pmid=15357213 |doi=10.2174/1566524043360096] Kinetoplasts are only found in protozoaof the class kinetoplastea. Kinetoplasts are usually adjacent to the organisms' flagellar basal bodyleading to the thought that they are tightly bound to the cytoskeleton.
Trypanosomes, a group of flagellated protozoans have a kinetoplast contained inside one large mitochondrion. "
Trypanosoma brucei", the parasite which causes African trypanosomiasis(African sleeping sickness), is an example of a Trypanosome with a kinetoplast. Its kinetoplast is easily visible in samples stained with DAPI, a fluorescentDNA stain.
Wikimedia Foundation. 2010.