Kinetoplast

Kinetoplast

A Kinetoplast is a disk-shaped mass of circular DNAs inside a large mitochondrion that contains many copies of the mitochondrial genome. [cite journal |author=Shapiro TA, Englund PT |title=The structure and replication of kinetoplast DNA |journal=Annu. Rev. Microbiol. |volume=49 |pages=117–43 |year=1995 |pmid=8561456 |doi=10.1146/annurev.mi.49.100195.001001] [cite journal |author=Shlomai J |title=The structure and replication of kinetoplast DNA |journal=Curr. Mol. Med. |volume=4 |issue=6 |pages=623–47 |year=2004 |pmid=15357213 |doi=10.2174/1566524043360096] Kinetoplasts are only found in protozoa of the class kinetoplastea. Kinetoplasts are usually adjacent to the organisms' flagellar basal body leading to the thought that they are tightly bound to the cytoskeleton.

Trypanosomes, a group of flagellated protozoans have a kinetoplast contained inside one large mitochondrion. "Trypanosoma brucei", the parasite which causes African trypanosomiasis (African sleeping sickness), is an example of a Trypanosome with a kinetoplast. Its kinetoplast is easily visible in samples stained with DAPI, a fluorescent DNA stain.

References


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  • kinetoplast — kinetoplast. См. кинетопласт. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • kinetoplast — [ki net′ə plast΄, kinēt′ə plast΄] n. 〚 KINETO + PLAST〛 a cytoplasmic structure lying at the base of the flagellum in many flagellated protists * * * ki·net·o·plast (kə nĕtʹə plăst , nēʹtə , kī ) n. An independently replicating structure lying… …   Universalium

  • Kinetoplast — Kinetoplast, Besonderheit der zu den Protomonadida (Zooflagellata) gehörenden Trypanosomidae: DNA Anhäufung hinter dem Basalkörper der Geißel innerhalb des einzigen Mitochondriums …   Deutsch wörterbuch der biologie

  • kinetoplast — [ki net′ə plast΄, kinēt′ə plast΄] n. [ KINETO + PLAST] a cytoplasmic structure lying at the base of the flagellum in many flagellated protists …   English World dictionary

  • kinetoplast DNA — kinetoplast DNA. См. кинетопластная ДНК. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • kinetoplast — noun Etymology: International Scientific Vocabulary Date: 1925 a DNA containing organelle especially of trypanosomes usually found in an elongated mitochondrian located adjacent to the basal body …   New Collegiate Dictionary

  • kinetoplast — (ki ne to plast) A special structure in the mitochondrion of kinetoplastid protozoa. It contains the mitochondrial DNA …   Dictionary of microbiology

  • kinetoplast — Mass of mitochondrial DNA, usually adjacent to the flagellar basal body, in flagellate protozoa …   Dictionary of molecular biology

  • kinetoplast — noun A disk shaped mass of circular DNA inside a large mitochondrion, found specifically in protozoa of the class Kinetoplastea (kinetoplastids) …   Wiktionary

  • kinetoplast — An intensely staining rod , disc , or spherical shaped extranuclear DNA structure found in parasitic flagellates (family Trypanosomatidae) near the base of the flagellum, posterior to the blepharoplast, and often at right angles to the …   Medical dictionary

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