CD155

Protein
Name=CD155
Symbol=CD155


caption= Poliovirus (in red and blue) bound to CD155 (purple)
AltSymbols=HVED, Necl-5, NECL5, Tage4
HGNCid=
Chromosome=19
Arm=q
Band=13.2
LocusSupplementaryData=
ECnumber=
OMIM=173850
EntrezGene=5817
RefSeq=NM_006505
UniProt=P15151

CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. [cite journal |author=Mendelsohn CL, Wimmer E, Racaniello VR |title=Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily |journal=Cell |volume=56 |issue=5 |pages=855–65 |year=1989 |pmid=2538245 |doi=] Commonly known as "Poliovirus Receptor" (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells.cite journal |author=Maier MK, Seth S, Czeloth N, "et al" |title=The adhesion receptor CD155 determines the magnitude of humoral immune responses against orally ingested antigens |journal= |volume= |issue= |pages= |year=2007 |pmid=17621371 |doi=10.1002/eji.200737072] The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses.

References