Gene Tools

Gene Tools

Gene Tools, LLC is a limited liability company located in Philomath, Oregon, United States that manufactures Morpholino antisense oligos and delivery reagents [cite journal | last = Summerton | first = JE | year = 2005 | title = Endo-porter: a novel reagent for safe, effective delivery of substances into cells. | journal = Ann N Y Acad Sci | volume = 1058 | pages = 62–75 | url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16394126 | format = Pubmed | doi = 10.1196/annals.1359.012 | pmid = 16394126 ] [cite journal | last = Morcos | first = PA | year = 2001 | title = Achieving efficient delivery of morpholino oligos in cultured cells. | journal = Genesis | volume = 30 | pages = 94–102 | url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=11477682 | format = Pubmed | doi = 10.1002/gene.1039 ] . Gene Tools was founded in 1997 and began regularly shipping custom-sequence Morpholino oligos in 2000. The manager and general partner, Dr. Jim Summerton, is a pioneer in antisense research [cite journal | last = Summerton | first = JE | year = submitted 1973, published 1979 | title = Intracellular inactivation of specific nucleotide sequences: a general approach to the treatment of viral diseases and virally-mediated cancers. | journal = Theoretical Biology | volume = 78 | pages = 77–99 | doi = 10.1016/0022-5193(79)90327-8 ] , conceived of and was co-inventor of the Morpholino antisense oligo structural type [cite journal | last = Summerton | first = J | coauthors = Weller D | year = 1997 | title = Morpholino Antisense Oligomers: Design, Preparation and Properties. | journal = Antisense & Nucleic Acid Drug Development | volume = 7* | pages = 187–95 | url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9212909 | format = Pubmed ] and founded the first antisense therapeutics company, AVI Bio Pharma Inc. (formerly AntiVirals Inc.).

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External links

* [http://www.gene-tools.com Gene Tools]


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