Humouse

A humouse is an immunodeficient mouse reconstituted with a human immune system. Although conventional mouse models have allowed for an increased understanding of mammalian immune systems, sometimes this knowledge cannot be directly applied to humans due to biological differences between the two species.

Humice could theoretically be used as novel pre-clinical models of the human immune system, with uses including assessing vaccine efficacy.

ee also

* Immunology
* Knockout mouse