MAOA

MAOA

Monoamine oxidase A, also known as MAOA, is a human gene.

This gene encodes monoamine oxidase A, an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the mitochondrial outer membrane. The gene is adjacent to a related gene on the opposite strand of chromosome X. Mutation in this gene results in monoamine oxidase deficiency, or Brunner syndrome. [cite web | title = Entrez Gene: MAOA monoamine oxidase A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4128| accessdate = ]

A study, by Guang Guo, Michael Roettger and Tianji Chi at the University of North Carolina Chapel Hill, claims to have found a correlation with the 2R variant of the gene and the likelihood of committing crime or violence. [ [http://www.asanet.org/galleries/default-file/Aug08ASRFeature.pdf Guo, Roettger & Chi article in American Sociological Review] ] [ [http://www2.asanet.org/journals/asr/abstracts.html Guo, Roettger & Chi abstract] ]

ee also

* Monoamine oxidase

References

Further reading

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citations =
*cite journal | author=Edmondson DE, Binda C, Mattevi A |title=The FAD binding sites of human monoamine oxidases A and B. |journal=Neurotoxicology |volume=25 |issue= 1-2 |pages= 63–72 |year= 2004 |pmid= 14697881 |doi= 10.1016/S0161-813X(03)00114-1
*cite journal | author=Craig IW |title=The importance of stress and genetic variation in human aggression. |journal=Bioessays |volume=29 |issue= 3 |pages= 227–36 |year= 2007 |pmid= 17295220 |doi= 10.1002/bies.20538

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