Pancreatic elastase

Pancreatic elastase

protein
Name = elastase 1, pancreatic
caption =


width =
HGNCid = 3308
Symbol = ELA1
AltSymbols =
EntrezGene = 1990
OMIM = 130120
RefSeq = NM_001971
UniProt = Q9UNI1
PDB =
ECnumber = 3.4.21.36
Chromosome = 12
Arm =
Band =
LocusSupplementaryData =

Pancreatic elastase is a form of elastase formed in the pancreas.

From recent research, it appears that of the two, ELA-1 is not transcribed into a protein. [cite journal |author=Rose S, MacDonald R |title=Evolutionary silencing of the human elastase I gene (ELA1) |journal=Hum Mol Genet |volume=6 |issue=6 |pages=897–903 |year=1997 |pmid=9175736 |doi=10.1093/hmg/6.6.897]

Clinical significance

Fecal elastase is used as a measure of pancreatic status.

References

External links

*


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • pancreatic elastase II — pan·cre·at·ic elas·tase II (pan″kre atґik e lasґtās) [EC 3.4.21.71] a serine endopeptidase that catalyzes the cleavage of peptide bonds, preferentially clearing on the carboxyl side of leucine, methionine, and phenylalanine residues.… …   Medical dictionary

  • elastase — A serine proteinase hydrolyzing elastin; other e. like enzymes have been identified ( e.g., pancreatic e. [pancreatopeptidase E] and leukocyte e. [lysosomal or neutrophil e.]) with different sequences and kinetic parameters; all have fairly broad …   Medical dictionary

  • Elastase — In molecular biology, elastase is an enzyme from the class of proteases (peptidases) , that break down proteins. Forms and classificationThere exist two human genes for elastase: * Pancreatic elastase (ELA 1) * Neutrophil elastase (ELA… …   Wikipedia

  • Pancreatic juice — is a juice produced by the pancreas. It contains a variety of enzymes, including trypsinogen, chymotrypsinogen, elastase, carboxypeptidase, pancreatic lipase, and amylase.Pancreatic juice is alkaline in nature due to the high concentration of… …   Wikipedia

  • elastase — noun Etymology: elastin + ase Date: 1949 an enzyme especially of pancreatic juice that digests elastin …   New Collegiate Dictionary

  • elastase — /i las tays, taz/, n. Biochem. a pancreatic protease that catalyzes the hydrolysis of elastin and other related proteins to polypeptides and amino acids. [1945 50; ELAST(IN) + ASE] * * * …   Universalium

  • elastase — noun a pancreatic enzyme that catalyzes the hydrolysis of elastin • Hypernyms: ↑enzyme …   Useful english dictionary

  • Fecal elastase — refers to the testing of the concentration of the pancreatic elastase 1 enzyme found in fecal matter with an enzyme linked immunosorbent assay (ELISA). Results of this test can give a good indication of exocrine pancreatic status and is less… …   Wikipedia

  • Pankreas-Elastase — Masse/Länge Primärstruktur 241 Aminosäuren …   Deutsch Wikipedia

  • Exocrine pancreatic insufficiency — Infobox Disease Name = PAGENAME Caption = DiseasesDB = ICD10 = ICD9 = ICD9|577.8 ICDO = OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = D010188 Exocrine pancreatic insufficiency (EPI) is the inability to properly digest food due to …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”