- Adams-Stokes syndrome
Infobox_Disease
Name = PAGENAME
Caption =
DiseasesDB = 12443
ICD10 = ICD10|I|45|9|i|30
ICD9 = ICD9|426.9
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj =
eMedicineTopic =
MeshID = D000219The term Stokes-Adams Attack refers to a sudden, transient episode of syncope, occasionally featuringseizure s. It is named after two Irish physicians, [WhoNamedIt|synd|1158] Robert Adams (1791–1875) [R. Adams. Cases of Diseases of the Heart, Accompanied with Pathological Observations. Dublin Hospital Reports, 1827, 4: 353-453. ] andWilliam Stokes (1804–1877). [W. Stokes. Observations on some cases of permanently slow pulse. Dublin Quarterly Journal of Medical Science, 1846, 2: 73-85.]igns and symptoms
Prior to an attack, a patient may become pale, their heart rhythm experiences a temporary pause, and collapse may follow. Normal periods of unconsciousness last approximately thirty seconds; if seizures are present, they will consist of twitching after 15–20 seconds. Breathing continues normally throughout the attack, and so on recovery the patient becomes flushed as the heart rapidly pumps the oxygenated blood from the pulmonary beds into a systemic circulation which has become dilated due to hypoxia.cite book|last = Katz | first = Jason| authorlink = | coauthors = Patel, Chetan| title = Parkland Manual of Inpatient Medicine| publisher = FA Davis| date = 2006| location = Dallas, TX| pages = 903|]
As with any syncopal episode that results from a cardiac dysrhythmia, the faints do not depend on the patient's position. If they occur during sleep, the presenting symptom may simply be feeling hot and flushed on waking.
Diagnosis
Stokes-Adams attacks may be diagnosed from the history, with paleness prior to the attack and flushing after it particularly characteristic. The ECG will show asystole or
ventricular fibrillation during the attacks.Causes
The attacks are caused by loss of
cardiac output due to cardiacasystole ,heart block , or ventricular fibrillation. The resulting lack of blood flow to thebrain is responsible for the faint.Treatment
Initial treatment can be medical, involving the use of drugs like
isoproterenol (Isuprel ) andepinephrine (adrenaline). Definitive treatment is surgical, involving the insertion of a pacemaker – most likely one with sequential pacing such as aDDI mode as opposed to the olderVVI mechanisms.Prognosis
If undiagnosed (or untreated), Stokes-Adams attacks have a 50% mortality within a year of the first episode. The prognosis following treatment is very good.
References
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