Uroguanylin

protein
Name=guanylate cyclase activator 2B (uroguanylin)
caption=


width=
HGNCid=4683
Symbol=GUCA2B
AltSymbols=
EntrezGene=2981
OMIM=601271
RefSeq=NM_007102
UniProt=Q16661
PDB=
ECnumber=
Chromosome=1
Arm=p
Band=34
LocusSupplementaryData=-p33

Uroguanylin is a 16 amino acid peptide that is secreted by enterochromaffin cells in the duodenum and proximal small intestine. Guanylin acts as an agonist of the guanylyl cyclase receptor GC-C and regulates electrolyte and water transport in intestinal and renal epithelia.

ee also

* Natriuretic peptide

External links

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