Immunoglobulin D

Immunoglobulin D

Immunoglobulin D (IgD) is an antibody isotype that makes up about 1% of proteins in the plasma membranes of immature B-lymphocytes where it is usually coexpressed with another cell surface antibody called IgM. IgD is also produced in a secreted form that is found in very small amounts in blood serum. Secreted IgD is produced as a monomeric antibody with two heavy chains of the delta (δ) class, and two Ig light chains.

Function

IgD's function is to signal when the young B cells in the spleen are ready to be activated. By being activated, they are ready to take part in the defense of the body in the immune system.

ee also

* Antibody
* IgM, IgA, IgE, IgG

External links

*


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  • immunoglobulin — im mu*no*glob ulin ([i^]m m[ u]*n[ o]*gl[o^]b [ u]*l[i^]n) n. (1953) any one of a class of globular proteins which are antibodies and are produced by the immune system in animals. Note: The immunoglobulins form a series of related proteins which… …   The Collaborative International Dictionary of English

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  • immunoglobulin D — immunoglobulin im mu*no*glob ulin ([i^]m m[ u]*n[ o]*gl[o^]b [ u]*l[i^]n) n. (1953) any one of a class of globular proteins which are antibodies and are produced by the immune system in animals. Note: The immunoglobulins form a series of related… …   The Collaborative International Dictionary of English

  • immunoglobulin G — immunoglobulin im mu*no*glob ulin ([i^]m m[ u]*n[ o]*gl[o^]b [ u]*l[i^]n) n. (1953) any one of a class of globular proteins which are antibodies and are produced by the immune system in animals. Note: The immunoglobulins form a series of related… …   The Collaborative International Dictionary of English

  • immunoglobulin M — immunoglobulin im mu*no*glob ulin ([i^]m m[ u]*n[ o]*gl[o^]b [ u]*l[i^]n) n. (1953) any one of a class of globular proteins which are antibodies and are produced by the immune system in animals. Note: The immunoglobulins form a series of related… …   The Collaborative International Dictionary of English

  • Immunoglobulin M — Immunoglobulin M, or IgM for short, is a basic antibody that is present on B cells. It is the primary antibody against A and B antigens on red blood cells. IgM is by far the physically largest antibody in the human circulatory system. tructure… …   Wikipedia

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  • immunoglobulin — immunoglobulin. См. иммуноглобулин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • immunoglobulin D — n IGD …   Medical dictionary

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