- Genipin
Chembox new
ImageFile = genipin.png
ImageSize = 180px
IUPACName = Methyl ("1R,2R,6S")-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo [4.3.0] nona-4,8-diene-5-carboxylate
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Section1 = Chembox Identifiers
CASNo = 6902-77-8
PubChem = 442424
SMILES = COC(=O)C1=CO [C@H] ( [C@H] 2 [C@@H] 1CC=C2CO)O
Section2 = Chembox Properties
Formula = C11H14O5
MolarMass = 226.226 g/mol
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Section3 = Chembox Hazards
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Autoignition =Genipin is the active compound found in the
gardenia fruit extract, which is used intraditional Chinese medicine to relieve the symptoms of type 2 diabetes. Research conducted at theBeth Israel Deaconess Medical Center andHarvard Medical School indicated that the chemical is indeed effective.Genipin is an aglycone derived from an
iridoid glycoside calledgeniposide present in fruit of "Gardenia jasminoides ". Genipin is an excellent naturalcross-link er for proteins, collagen, gelatin, and chitosan cross-linking. It has a low acute toxicity, with LD50 i.v. 382 mg/kg in mice, therefore, much less toxic thanglutaraldehyde and many other commonly used synthetic cross-linking regents. It is also used for pharmaceutical purposes, such as choleretic action for liver diseases control.External links
* [http://news.bbc.co.uk/1/hi/health/5052212.stm Chinese remedy 'treats diabetes'] (BBC News)
* [http://www.genipin.org/ CBC Genipin]
* [http://www.wou.edu/las/physci/ch350/Projects_2006/Vaandering/Genipin.htm Introduction of genipin]
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