Simkaniaceae

Taxobox
name = Simkaniaceae
regnum = Bacteria
phylum = Chlamydiae
classis = Chlamydiae
ordo = Chlamydiales
familia = Simkaniaceae
subdivision_ranks = Genera
subdivision = "Simkania"
"Fritschea"

Simkaniaceae is a family of bacteria in the order Chlamydiales, class Chlamydiae, phylum Chlamydiae, domain Bacteria. Species in this family have a chlamydia-like cycle of replication and their ribosomal RNA genes are 80–90% identical to ribosomal genes in the Chlamydiaceae. The Simkaniaceae are not recognized by monoclonal antibodies that are specific for Chlamydiaceae lipopolysaccharide. The family Simkaniaceae currently includes two genera: "Simkania" and "Fritschea". The type species is "Simkania negevensis", and its natural host is not known. It is readily grown in monolayers of eukaryotic Vero cells. Serological evidence and PCR indicate that "S. negevensis" is widespread among humans.

Two "Fritschea" species have been identified in insects. These are candidatus species because they only grow in insect bacteriocytes and have not been cultured in vitro. Whiteflies are the host of Candidatus "Fritschea bemisiae" (strain Falk). Scale insects are the host of Candidatus "Fritschea eriococci" (strain Elm).

"Simkania negevensis" and "Fritschea bemisiae" have a group I intron in the 23S rRNA, unlike other characterized chlamydial rRNA genes. The introns are closely related to group I introns in the 23S rRNA of chloroplasts and mitochondria in algae and amoebae.