- CURB-65
CURB-65 is a
clinical prediction rule that has been validated for predicting mortality incommunity-acquired pneumonia cite journal |author=Lim WS, van der Eerden MM, Laing R, "et al" |title=Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study |journal=Thorax |volume=58 |issue=5 |pages=377–82 |year=2003 |pmid=12728155 |doi=] and infection of any sitecite journal |author=Howell MD, Donnino MW, Talmor D, Clardy P, Ngo L, Shapiro NI |title=Performance of severity of illness scoring systems in emergency department patients with infection |journal=Academic emergency medicine : official journal of the Society for Academic Emergency Medicine |volume=14 |issue=8 |pages=709–14 |year=2007 |pmid=17576773 |doi=10.1197/j.aem.2007.02.036] . The CURB-65 is based on the earlier CURB scorecite journal |author=Lim WS, Macfarlane JT, Boswell TC, "et al" |title=Study of community acquired pneumonia aetiology (SCAPA) in adults admitted to hospital: implications for management guidelines |journal=Thorax |volume=56 |issue=4 |pages=296–301 |year=2001 |pmid=11254821 |doi=] and is recommended by theBritish Thoracic Society for the assessment of severity of pneumonia.cite journal |author= |title=BTS Guidelines for the Management of Community Acquired Pneumonia in Adults |journal=Thorax |volume=56 Suppl 4 |issue= |pages=IV1–64 |year=2001 |pmid=11713364 |doi=]The score is an for each of the risk factors measured. Each risk factor scores one point, for a maximum score of 5:
* confusion (defined as an AMT of 8 or less)
* urea greater than 7 mmol/l (Blood Urea Nitrogen > 19)
* respiratory rate of 30 breaths per minute or greater
* blood pressure less than 90 systolic or diastolic blood pressure 60 or less
* age 65 or olderPredicting death from pneumonia
The risk of death increases as the score increases:
* 0—0.7%
* 1—3.2%
* 2—13.0%
* 3—17.0%
* 4—41.5%
* 5—57.0%The CURB-65 has been compared to the
pneumonia severity index in predicting mortality from pneumonia.cite journal |author=Aujesky D, Auble TE, Yealy DM, "et al" |title=Prospective comparison of three validated prediction rules for prognosis in community-acquired pneumonia |journal=Am. J. Med. |volume=118 |issue=4 |pages=384–92 |year=2005 |pmid=15808136 |doi=10.1016/j.amjmed.2005.01.006]Predicting death from any infection
A
cohort study of patients with any type of infection (half of the patients had pneumonia), the risk of death increases as the score increases:
* 0 to 1 <5% mortality
* 2 to 3 < 10% mortality
* 4 to 5 15-30% mortalityReferences
External links
* [http://www.brit-thoracic.org.uk British Thoracic Society]
* [http://www.icumedicus.com/clinical_criteria/pneumonia_severity_score.php ICU Medicus Pneumonia Severity Score] - online calculator for the CURB-65
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