HC

HC may refer to:
* Hydrocarbon
* Homocapsaicin, a capsaicinoid
* Hospitality Club, the hospitality exchange network
* Hyperelastosis cutis (see hereditary equine regional dermal asthenia)
* Aero-Tropics Air Services' IATA airline designator
* WWE Hardcore Championship, now defunct title in World Wrestling Entertainment
* HyperCard, an ancient Macintosh hypermedia program that has been cloned by several companies.
* "Heathen Chemistry", the fifth album by British rock band Oasis
* Half cadence, in music.
* Hardcore punk, a music genre
* Honorary degree
* Hors catégorie, a French term used in cycle races to designate a climb that is "beyond categorization"
* Highway Contract, an outsourced United States Postal Service delivery method, formerly known as Star routes
* H/C, an abbreviation used to describe fanfiction