Crypts of Lieberkühn

Crypts of Lieberkühn

Infobox Anatomy
Name = PAGENAME
Latin = glandulae intestinales
GraySubject = 248
GrayPage = 1174


Caption = An intestinal gland from the human intestine.


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DorlandsPre = g_06
DorlandsSuf = 12392417
The crypts of Lieberkühn (or intestinal glands) are glands found in the epithelial lining of the small intestine and colon. Named after the 18th-century German anatomist Johann Nathanael Lieberkühn, the crypts secrete various enzymes, including sucrase and maltase, along with endopeptidases and exopeptidases. Loss of proliferation control in the crypts is thought to lead to colorectal cancer.

The basal portion of the Crypt contains multipotent stem cells. At each mitosis one daughter remains a stem cell while the other differentiates and migrates up the side of the crypt and eventually the villus. Goblet cells are among the cells produced in this fashion.


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External links

* [http://www.trinity.edu/rblyston/MicroA/Lectures/L24-html/sld025.htm Illustration at trinity.edu]
* [http://www.kumc.edu/instruction/medicine/anatomy/histoweb/gitract/gi18a.htm Illustration at kumc.edu]
* [http://w3.uokhsc.edu/histology/Glass%20slides/54_04.jpgIllustration at uokhsc.edu]
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Look at other dictionaries:

  • crypts of Lieberkuhn — Lieberkuhn s glands Lie ber*k[ u]hn s glands (l[=e] b[ e]r*k[.u]nz gl[a^]ndz ) n. [See {Lieberk[ u]hn}.] (Anat.) The simple tubular glands of the small intestines; called also {crypts of Lieberk[ u]hn}. [1913 Webster] …   The Collaborative International Dictionary of English

  • crypts of Lieberkühn — Lieberkühn s glands …   The new mediacal dictionary

  • crypts of Lieberkühn — see Lieberkühn s glands …   Medical dictionary

  • Lieberkühn's glands — (crypts of Lieberkühn) simple tubular glands in the mucous membrane of the intestine. In the small intestine they lie between the villi. They are lined with columnar epithelium in which various types of secretory cells are found. In the large… …   Medical dictionary

  • Lieberkühn's glands — crypts of Lieberkühn simple tubular glands in the mucous membrane of the intestine. In the small intestine they lie between the villi. They are lined with columnar epithelium in which various types of secretory cells are found. In the large… …   The new mediacal dictionary

  • Lieberkuhn's glands — Lie ber*k[ u]hn s glands (l[=e] b[ e]r*k[.u]nz gl[a^]ndz ) n. [See {Lieberk[ u]hn}.] (Anat.) The simple tubular glands of the small intestines; called also {crypts of Lieberk[ u]hn}. [1913 Webster] …   The Collaborative International Dictionary of English

  • Железы Либеркюновы (Lieberkuhn'S Glands), Крипты Либеркюновы (Crypts Of Lieberkuhn) — трубчатые углубления в собственной пластинке слизистой оболочки кишечника. В тонкой кишке они располагаются между ворсинками. Либесркюновы крипты выстланы слоем столбчатого эпителия, в котором присутствуют различные виды клеток (каемчатые,… …   Медицинские термины

  • Lieberkühn — Johann N., German anatomist, 1711–1756. See crypts of L., under crypt, L. follicles, under follicle, L. glands, under gland …   Medical dictionary

  • crypt of Lieberkuhn — crypt of Lie·ber·kühn lē bər .k(y)ün, .kuen n any of the tubular glands of the intestinal mucous membrane called also gland of Lieberkühn, intestinal gland, Lieberkühn s gland Lie·ber·kühn lē bər .kuen J …   Medical dictionary

  • Johann Nathanael Lieberkühn — (September 5, 1711, Berlin October 7. 1756, Berlin) was a German physician. His middle name is sometimes misspelled Nathaniel .The Crypts of Lieberkühn (intestinal glands) are named after him.External… …   Wikipedia

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