Gabriel-Colman rearrangement

Gabriel-Colman rearrangement

The Gabriel-Colman rearrangement is the chemical reaction of phthalimidoacetic esters (2) with strong base to form substituted isoquinolines (3). [Gabriel, S.; Colman, J. "Ber." 1900, "33", 980 & 996 & 2630.] [Gabriel, S.; Colman, J. "Ber." 1902, "35", 2421.] [Allen, C. F. H. "Chem. Rev." 1950, "47", 275. (Review)] [Hill, J. H. M. "J. Org. Chem." 1965, "30", 620.]

References

ee also

*Dieckmann reaction


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