Effective renal plasma flow

Effective renal plasma flow

Effective renal plasma flow (eRPF) is a measure used in renal physiology to calculate renal plasma flow (RPF) and hence estimate renal function.

: eRPF = RPF imes extraction ratio [ [http://www.lib.mcg.edu/edu/eshuphysio/program/section7/7ch04/7ch04p28.htm Sect. 7, Ch. 4: Measurement of Renal Plasma Flow; Renal Clearance of PAH ] ]

Where extraction ratio is the ratio of compound entering the kidney that got excreted into the final urine. [ [http://student.ttuhsc.edu/2/files/phys030905.doc Renal Mathematics] Texas Tech University Health Sciences Center ]

When using a compound with an extraction ratio near 1, such as para-aminohippurate (PAH), then eRPF is almost equal to RPF. Therefore, PAH clearance is a method to estimate renal plasma flow.

References


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