Thyronamine

Chembox new
ImageFile = Thyronamine-2D-skeletal.png ImageSize = 300px
ImageFile2 = Thyronamine3d.png ImageSize2 = 300px
IUPACName =
OtherNames =
Section1 = Chembox Identifiers
CASNo = 500-78-7
PubChem = 3083601
SMILES =
MeSHName = thyronamine
Section2 = Chembox Properties
Formula = C₁₄H₁₅NO₂
MolarMass = 229.274 g mol⁻¹
Appearance =
Density =
MeltingPt =
BoilingPt =
Section3 = Chembox Hazards
Solubility =
MainHazards =
FlashPt =
Autoignition =

Thyronamine refers both to a molecule, and to derivatives of that molecule: a family of decarboxylated and deiodinated metabolites of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3).

The group includes:

* Thyronamine (T0AM)
* 3-Iodothyronamine (T1AM), which is the most notable one as it is a trace amine found in the nervous system. It is a possible candidate for the natural ligand of the trace amine-associated receptor TAAR1 (TAR1), a G protein-coupled receptor located in the cell membrane.
* 3,5-Diiodothyronamine (T2AM)
* 3,5,3'-Triiodothyronamine (T3AM)

See also

* Thyroid hormone