Organum vasculosum of the lamina terminalis

Organum vasculosum of the lamina terminalis

Infobox Brain
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The organum vasculosum of the lamina terminalis (OVLT) (or supraoptic crest) is one of the circumventricular organs of the brain . Other circumventricular organs are the subfornical organ (SFO) and the area postrema in the brainstem.

AV3V region

The OVLT and the SFO are both strongly interconnected with the median preoptic nucleus of the hypothalamus (the nucleus medianus), and together these three structures comprise the so called "AV3V" region - the region anterior and ventral to the third ventricle. The AV3V region is very important in the regulation of fluid and electrolyte balance, by controlling thirst, sodium excretion, blood volume regulation, and vasopressin secretion.

Function

The OVLT is outside the blood brain barrier, and so neurons in this region can respond to factors that are present in the systemic circulation.

Some neurons in the OVLT are osmoreceptors, being sensitive to the osmotic pressure of the blood. These neurons project to the supraoptic nucleus and paraventricular nucleus to regulate the activity of vasopressin-secreting neurons. These neurons also project to the nucleus medianus (also called the medial preoptic nucleus) which is involved in controlling thirst.

ee also

* lamina terminalis

External links

* http://www.sci.uidaho.edu/med532/lamina.htm


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  • Organum vasculosum laminae terminalis — Das Organum vasculosum laminae terminalis (OVLT) ist ein zirkumventrikuläres Organ. Es liegt rostral des Hypothalamus und ist ein Teil der Lamina terminalis. Funktion Die Funktion des OVLT ist noch nicht vollständig aufgeklärt. Man nimmt an, dass …   Deutsch Wikipedia

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  • organ — Any part of the body exercising a specific function, as of respiration, secretion, or digestion. SYN: organum [TA], organon. [L. organum, fr. G. organon, a tool, instrument] accessory organs 1. SYN …   Medical dictionary

  • Thirst — is the craving for liquids, resulting in the basic instinct of humans or animals to drink. It is an essential mechanism involved in fluid balance. It arises from a lack of fluids and/or an increase in the concentration of certain osmolites such… …   Wikipedia

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