GDB Human Genome Database

GDB Human Genome Database

The GDB Human Genome Database is a community curated collection of human genomic data. What set GDB apart from other biological databases, was its use of world-class leaders in human genetics to act as curators for the data. In order to ensure a high degree of quality, records within GDB were subjected to a process of peer-review, not unlike a traditional publication. Due to the International collaboration which made up the human genome project, GDB received funding from numerous sources in both Europe and Asia.

History

In 1989 the Howard Hughes Medical Institute provided funding to establish a central repository for human genetic mapping data. This project ultimately resulted in the creation of the GDB Human Genome DataBase in 1990. It was a key database in the human genome project.

Established under the leadership of Dr.'s Peter Person and Dick Lucier, GDB received significant financial support from the US Department of Energy and the National Institutes of Health. Located at the Johns Hopkins University School of Medicine, GDB became a source of high quality mapping data which were made available both on-line as well as through numerous printed publications.

In 1998, the change of focus in the human genome project redirected funds which were previously available for GDB. However that same year, Dr. A. Jamie Cuticchia obtained funding from Canadian public and private sources to continue the operations of GDB. While the data curation continued to be performed at Johns Hopkins, GDB central operations were moved to The Hospital for Sick Children in Toronto, Ontario, Canada.

In 2003 RTI International became the new host for GDB where it continued to be maintained as a public resource for high quality genetic and genomic information.

On June 1, 2008 RTI International shut down GDB operations.

External links


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Genome Database — The Genome Database (GDB) is the official central repository for genomic mapping data resulting from the Human Genome Initiative. It was established at Johns Hopkins University in Baltimore, Maryland, USA in 1990. In 1999, the Bioinformatics… …   Medical dictionary

  • GDB — Genome Database (Medical » Human Genome) * Guide Dogs for the Blind (Community » Non Profit Organizations) * Great Diving Beetle (Miscellaneous » Food) …   Abbreviations dictionary

  • GDB/OMIM — Genome Database/Online Mendelian Inheritance in Man (Medical » Human Genome) …   Abbreviations dictionary

  • GDB — The Genome Database (GDB), the official central repository for genomic mapping data resulting from the Human Genome Initiative. Established at Johns Hopkins University in Baltimore, Maryland, USA in 1990. In 1999, the Bioinformatics… …   Medical dictionary

  • Biological database — Biological databases are libraries of life sciences information, collected from scientific experiments, published literature, high throughput experiment technology, and computational analyses. They contain information from research areas… …   Wikipedia

  • The 1000 Genomes Project — The 1000 Genomes Project, launched in January 2008, is an international research effort to establish by far the most detailed catalogue of human genetic variation. Scientists plan to sequence the genomes of at least one thousand anonymous… …   Wikipedia

  • A. Jamie Cuticchia — A. Jamie Cuticchia, Ph.D. (born December 28, 1966) is a leader in human genome informatics. He earned his B.A. in Biological Sciences from the University of Maryland, Baltimore and his Ph.D. in Genetics from the University of Georgia.He was the… …   Wikipedia

  • ABCA4 — ATP binding cassette, sub family A (ABC1), member 4, also known as ABCA4, is a human gene.cite web | title = Entrez Gene: ABCA4 ATP binding cassette, sub family A (ABC1), member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

  • ABCD3 — ATP binding cassette, sub family D (ALD), member 3, also known as ABCD3, is a human gene.cite web | title = Entrez Gene: ABCD3 ATP binding cassette, sub family D (ALD), member 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

  • Sonic hedgehog — homolog (SHH) is one of three proteins in the mammalian hedgehog family, the others being desert hedgehog (DHH) and Indian hedgehog (IHH). SHH is the best studied ligand of the hedgehog signaling pathway. It plays a key role in regulating… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”