U.S. Route 11E

Infobox U.S. Route
article_route=11E
length_mi=120
length_km=
yrcom=1929
direction_a=South
direction_b=North
from=
to=

U.S. Route 11E is one of two routes carrying U.S. Route 11 between Knoxville, Tennessee and Bristol, Virginia in the United States. (The other is U.S. Route 11W.) From 1926 to 1929, US 11E was U.S. Route 511.

Unsigned State Route 9 is overlaid on US 11E in Tennessee.

The southern terminus is in east Knoxville, Tennessee at US 11, from which it splits, and U.S. Route 70, which is concurrent with US 11 and US 11E, until US 70 and US 25W split off together farther east in Knox County. (US 25W begins its concurrency with US 11E and US 70 when US 25W ends its concurrency with I-40.)

The northern terminus is U.S. Route 11, U.S. Route 19, U.S. Route 11W, U.S. Route 421, and Virginia Route 381 in Bristol, Virginia.