Theodore Puck

Theodore Puck

Theodore Puck (born September 24, 1916 - died November 6, 2005) was an American geneticist born in Chicago, Illinois. He attended Chicago public schools and obtained his bachelors and masters degree from the University of Chicago.

Puck was an early pioneer of "somatic cell genetics" and single-cell plating ( i.e. "cloning" .) This work allowed the genetics of human and other mammalian cells to be studied in detail. Pucks key work ultimately made modern genetics, such as the human genome and other mammalian genome projects, possible.

Puck made many basic discoveries in several areas. His team which found that humans had 46 chromosomes rather than 48 which had earlier been believed. He developed the CHO cell line from chinese hamster ovarian cells for this work. These cells are still widely utilized in the biopharmaceutical industry. Puck studied X-rays and cellular mutations. He also isolated and studied cellular mutations.

Puck has won a number of honors for his work most notably the Albert Lasker Award for Basic Medical Research in 1958. In 1973 he was awarded the Louisa Gross Horwitz Prize from Columbia University together with Renato Dulbecco and Harry Eagle. Dulbecco won the Nobel Prize in medicine in 1975.He also founded the Eleanor Roosevelt Institute at the University of Denver where he was an Emeritus Professor. A member of the National Academy of Science since 1960, Puck published more than 200 papers on topics including Alzheimer's Disease and Downs Syndrome, and optimising radiotherapy dosages for the treatment of cancer.

He died following complications from a broken hip.

References

* [http://www.eri.du.edu/faculty.cfm?ID=tpuck Puck's page at the Eleanor Roosevelt Institute]

* "Theodore T. Puck." "Notable Scientists: From 1900 to the Present" Gale Group, 2001 Reproduced in Biography Resource Center. Farmington Hills, Mich.: Thomson Gale. 2005

* [http://www.sciencedaily.com/upi/index.php?feed=Science&article=UPI-1-20051111-13284400-bc-us-puck-obit-crn.xml "Science Daily" obituary November 11, 2005]

* [http://rockymountainnews.com/drmn/local/article/0,1299,DRMN_15_4223267,00.html "Rocky Mountain News", obituary November 9, 2005]

* [http://www.tamu.edu/ccbn/dewitt/manzanar/updates.htm Tribute by Dr. Gordon Sato & colleagues, In Vitro Cell. Devel. Biol-Animal, 2006]

External links

* [http://www.cumc.columbia.edu/horwitz/ The Official Site of Louisa Gross Horwitz Prize]


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