Macroglobulinemia

Macroglobulinemia

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ICD9 = ICD9|273.3
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MeshID = D008258

Macroglobulinemia is the presence of increased levels of macroglobulins in the circulating blood.A plasma cell dyscrasia resembling leukemia with cells of lymphocytic, plasmacytic, or intermediate morphology, which secrete an immunoglobulin M monoclonal component. There is diffuse infiltration of bone marrow and also, in many cases, of the spleen, liver, or lymph nodes. The circulating macroglobulin produces symptoms of hyperviscosity syndrome: weakness, fatigue, bleeding disorders, and visual disturbances. Peak incidence is in the sixth and seventh decades. (Dorland, 28th ed)

ee also

* Waldenström macroglobulinemia


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  • macroglobulinemia — f. hemat. Incremento anormal en la sangre de gammaglobulina M (de alto peso molecular); puede aparecer sin síntomas o ser esencial (macroglobulinemia de Waldenström). Medical Dictionary. 2011 …   Diccionario médico

  • macroglobulinemia — A condition in which the blood contains high levels of large proteins and is too thick to flow through small blood vessels. One type is Waldenstrom macroglobulinemia, which is a type of cancer …   English dictionary of cancer terms

  • macroglobulinemia de Waldenström — f. hemat. Macroglobulinemia que afecta principalmente a varones ancianos ocasionada por una proliferación clonal de linfocitos B que segregan grandes cantidades de IgM. Los síntomas que provoca son astenia, debilidad, alteraciones visuales,… …   Diccionario médico

  • Macroglobulinemia de Waldenstrom — Waldenström s macroglobulinemia Clasificación y recursos externos CIE 10 C88.0 CIE 9 273.3 …   Wikipedia Español

  • Macroglobulinemia, Waldenstrom — A chronic low grade (indolent) type of lymphoma due to a malignant clone of plasma cells. These plasma cells multiply out of control, invade the bone marrow, lymph nodes, and spleen, and characteristically produce huge amounts of a large sized… …   Medical dictionary

  • macroglobulinemia de Waldenström — Eng. Waldenström s macroglobulinemia Síndrome de hiperviscosidad que cursa con paraproteinemia y presencia a nivel retiniano de dilatación venosa, segmentación y tortuosidad vascular, hemorragias retinianas superficiales y profundas, exudados… …   Diccionario de oftalmología

  • macroglobulinemia — noun Etymology: New Latin Date: 1949 a disorder characterized by increased blood serum viscosity and the presence of macroglobulins in the serum • macroglobulinemic adjective …   New Collegiate Dictionary

  • macroglobulinemia — mac·ro·glob·u·lin·e·mi·a (măk rō glŏb yə lə nēʹmē ə) n. A condition marked by an abnormally high concentration of macroglobulins in the blood serum. * * * …   Universalium

  • macroglobulinemia — noun The presence of high levels of macroglobulins in the blood …   Wiktionary

  • macroglobulinemia — The presence of increased levels of macroglobulins in the circulating blood. Waldenström m. m. occurring in elderly persons, characterized by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anemia, increased… …   Medical dictionary

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