- Perilymph
Perilymph is an extracellular fluid located within the
cochlea (part of theear ) in 2 of its 3 compartments; thescala tympani andscala vestibuli . The ionic composition of perilymph is comparable to that of plasma andcerebrospinal fluid . The major cation ofperilymph issodium .Perilymph vs. endolymph
The third compartment of the ear, the
cochlear duct (or scala media) containsendolymph . Perilymph and endolymph have unique ionic compositions suited to their functions in regulating electrochemical impulses of hair cells. The electric potential of endolymph is ~80-90 mV more positive than perilymph. [cite journal |author=Konishi T, Hamrick PE, Walsh PJ |title=Ion transport in guinea pig cochlea. I. Potassium and sodium transport |journal=Acta Otolaryngol. |volume=86 |issue=1-2 |pages=22–34 |year=1978 |pmid=696294 |doi=]Clinical significance
It has also been suggested that perilymph and endolymph participate in a unidirectional flow that is interrupted in
Meniere's disease .External links
* http://oto.wustl.edu/cochlea/intro3.htm
References
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