Rathke's pouch

Rathke's pouch

Infobox Embryology
Name = PAGENAME
Latin =
GraySubject = 275
GrayPage = 1277


Caption = Sketches in profile of two stages in the development of the human digestive tube.


Caption2 =
CarnegieStage = 10
Precursor =
GivesRiseTo = anterior pituitary
System =
MeshName =
MeshNumber =
DorlandsPre = p_31
DorlandsSuf = 12662673

In embryogenesis, Rathke's pouch is a depression in the roof of the developing mouth in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary, a part of the endocrine system.

Development

The pouch eventually loses its connection with the pharynx giving rise to the anterior pituitary. The anterior wall of Rathke's pouch proliferates, filling most of the pouch to form "pars distalis" and "pars tuberalis". The posterior wall forms "pars intermedia".

In some organisms (humans being a notable exception), the proliferating anterior wall does not fully occupy Rathke's pouch, leaving a remnant (Rathke's cleft) between the "pars distalis" and "pars intermedia".

Clinical significance

Rathke's pouch may also persist as cysts (craniopharyngioma) within the "pars intermedia".

Eponym

It is named for Martin Rathke. [WhoNamedIt|synd|3564] [M. H. Rathke. Entwicklungsgeschichte der Natter (Coluber natrix). Königsberg, Bornträger, 1839.]

References

External links

*
*
* [http://www.cushings-help.com/endo42.gifDiagram at cushings-help.com]
* http://www.lib.mcg.edu/edu/eshuphysio/program/section5/5ch2/s5ch2_2.htm


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  • Rathke's pouch — Rath·ke s pouch rät kəz n a pouch of ectoderm that grows out from the upper surface of the embryonic stomodeum and gives rise to the adenohypophysis of the pituitary gland called also Rathke s pocket Rathke Martin Heinrich (1793 1860) German… …   Medical dictionary

  • rathke's pouch — ˈrätkəz noun also rathke s pocket Usage: usually capitalized R Etymology: after Martin H. Rathke died 1860 German anatomist : a pouch of ectoderm that grows out from the upper surface of the embryonic stomodaeum and gives rise to the anterior… …   Useful english dictionary

  • Rathke's pouch — /raht keuhz/, Embryol. an invagination of stomodeal ectoderm developing into the anterior lobe of the pituitary gland. Also called Rathke s pocket. [1940 45; named after Martin Heinrich Rathke (1793 1860), German anatomist] * * * …   Universalium

  • Rathke's pouch — an embryonic invagination of the stomodeal ectoderm (roof of the embryonic mouth) which migrates dorsally to come into contact with diencephalon. It differentiates into the anterior pituitary gland or adenohypohysis. It becomes a blind naso… …   Dictionary of ichthyology

  • Rathke's pouch — see craniopharyngioma …   The new mediacal dictionary

  • Rathke, Martin H — ▪ German anatomist born Aug. 25, 1793, Danzig, Prussia [now Gdańsk, Pol.] died Sept. 3, 1860, Königsberg [now Kaliningrad, Russia]       German anatomist who first described the gill slits and gill arches in the embryos of mammals and birds. He… …   Universalium

  • pouch of rathke — Usage: usually capitalized R : rathke s pouch …   Useful english dictionary

  • rathke's pocket — noun see rathke s pouch …   Useful english dictionary

  • Rathke cysts — Rathke cleft cysts groups of epithelial cells forming small colloid filled cysts in the pars intermedia of the pituitary gland; they are vestiges of Rathke pouch and are closely related to craniopharyngiomas. Called also craniobuccal c s and… …   Medical dictionary

  • Rathke tumor — Rathke pouch tumor craniopharyngioma …   Medical dictionary

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