DHH phosphatase family

DHH family
streptococcus mutans inorganic pyrophosphatase
Identifiers
Symbol	DHH
Pfam	PF01368
InterPro	IPR001667
SCOP	1i74
Available protein structures: Pfam structures PDB RCSB PDB; PDBe PDBsum structure summary

In molecular biology, the DHH phosphatase family is a family of phosphoesterases. The family includes Drosophila prune protein and bacterial RecJ exonuclease.^[1] The RecJ protein of Escherichia coli plays an important role in a number of DNA repair and recombination pathways. RecJ catalyses processive degradation of single-stranded DNA in a 5'-to-3' direction. Sequences highly related to those encoding RecJ can be found in many of the eubacterial genomes sequenced to date.^[2]

References

1. ^ Aravind L, Koonin EV (January 1998). "A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease". Trends Biochem. Sci. 23 (1): 17–9. PMID 9478130. 
2. ^ Rajman LA, Lovett ST (February 2000). "A thermostable single-strand DNase from Methanococcus jannaschii related to the RecJ recombination and repair exonuclease from Escherichia coli". J. Bacteriol. 182 (3): 607–12. PMC 94321. PMID 10633092. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=94321. 

This article includes text from the public domain Pfam and InterPro IPR001667