SPM

SPM may refer to:

* Statistical parametric mapping, a method for analysing data from functional neuroimaging studies
* South Park Mexican, aka SPM, (rapper) real name Carlos Coy.
* The city of San Pedro de Macoris, in The Dominican Republic
* The ISO 3166-1 3-letter country code and an abbreviation for Saint-Pierre and Miquelon
* Scanning probe microscopy
* Self-phase modulation
* Sijil Pelajaran Malaysia, the examination that students in Malaysia take at the age of 17 (Form 5)
* Sociedade Portuguesa de Matemática, the Portuguese Mathematical Society
* Summary for policymakers of the IPCC reports.
* Saint Peter-Marian High School
* "Super Paper Mario", a game released on Nintendo's Wii
*Summit Place Mall
* Somali Patriotic Movement, a faction of the Somali Civil War
* Department of Social and Preventive Medicine in Faculty of Medicine, University of Malaya
* Shock Pulse Method, which is a patented technique for using signals from rotating rolling bearings as the basis for efficient condition monitoring of machines
* Synaptic Package Manager
* Single Point Mooring is a mooring arrangement for tankers to Offload liquid/gas products