Rs7341475

Infobox Single nucleotide polymorphism
rsid = 7341475
gene = RELN
chromosome = 7
region = Intron 4
szgene_geneid = 18
szgene_polyid = 5691In genetics, rs7341475 is a single nucleotide polymorphism (SNP) in the "RELN" gene that codes the reelin protein. The gene is located in the fourth intron on chromosome 7.The gene has many more SNPs among its 65 exons and 64 introns, — even in intron 4 there are tens of SNPs. [Cite web
url = http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?showRare=on&chooseRs=all&go=Go&locusId=5649
title = SNP linked to Gene RELN
publisher = NCBI
accessdate = 2008-09-09]

The SNP is currently under investigation for a possible link to schizophrenia.A 2008 genome-wide association study pointed to that a variant of the SNP could elevate the risk for schizophrenia among women. [Cite journal
author = Sagiv Shifman, Martina Johannesson, Michal Bronstein, Sam X. Chen, David A. Collier, Nicholas J. Craddock, Kenneth S. Kendler, Tao Li, Michael O'Donovan, F. Anthony O'Neill, Michael J. Owen, Dermot Walsh, Daniel R. Weinberger, Cuie Sun, Jonathan Flint & Ariel Darvasi
title = Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women
journal = PLoS Genetics
volume = 4
issue = 2
pages = e28
year = 2008
month = February
doi = 10.1371/journal.pgen.0040028
pmid = 18282107 News:
* Cite news
url = http://www.mentalhelp.net/poc/view_doc.php?type=news&id=108022&cn=7
author = Eric Metcalf
title = Genetic Variant Found for Women's Schizophrenia
publisher = MentalHelp.net
date = 2008-02-19
accessdate = 2008-09-09
* Cite news
url = http://www.psychiatrymatters.md/headlines/fullpage.asp?C=45637397004821296296&xml=/headlines/2008/02_february/week_08/gene_variant_linked_to_female_schizophrenia.xml
title = Gene variant linked to female schizophrenia
publisher = PsychiatryMatters.md
date = 2008-02-25
accessdate = 2008-09-09]

Reference