Obligate carrier

Obligate carrier

An obligate carrier is an individual who may be clinically unaffected but who must carry a gene mutation based on analysis of the family history; usually applies to disorders inherited in an autosomal recessive and X-linked recessive manner.[1][2]

References

  1. ^ http://ghr.nlm.nih.gov/glossary=obligatecarrier
  2. ^ Robin L. Bennett (1999). The practical guide to the genetic family history. Wiley–Liss Ltd. pp. 54. ISBN 0471251542. 



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