Suplatast tosilate

Drugbox
IUPAC_name = [3- [4-(3-ethoxy-2-hydroxypropoxy)phenyl] amino] -3-oxopropyl] -dimethylsulfanium; 4-methylbenzenesulfonate


CAS_number = 94055-76-2
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PubChem = 71773
DrugBank =
chemical_formula =
C=23 | H=33 | N=1 | O=7 | S=2
molecular_weight = 499.64 g/mol
smiles = CCOCC(COC1=CC=C(C=C1)NC(=O)CC [S+] (C)C)O.CC1=CC=C(C=C1)S(=O)(=O) [O-]
bioavailability =
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legal_status = Rx-only
routes_of_administration = Oral

Suplatast tosilate (INN) is a Th2 cytokine inhibitorcite journal |author=Tamaoki J, Kondo M, Sakai N, "et al" |title=Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroid-dependent asthma: a double-blind randomised study. Tokyo Joshi-Idai Asthma Research Group |journal=Lancet |volume=356 |issue=9226 |pages=273–8 |year=2000 |month=July |pmid=11071181 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0140673600025010] which is used as an antiallergic drug.

References

*cite journal |author=Taniguchi H, Togawa M, Ohwada K, "et al" |title=Suplatast tosilate, a new type of antiallergic agent, prevents the expression of airway hyperresponsiveness in guinea pigs |journal=Eur. J. Pharmacol. |volume=318 |issue=2-3 |pages=447–54 |year=1996 |month=December |pmid=9016937 |doi= |url=
*cite journal |author=Sano Y |title= [Anti-inflammatory drugs for the treatment of bronchial hyperresponsiveness] |language=Japanese |journal=Nihon Kyobu Shikkan Gakkai Zasshi |volume=34 Suppl |issue= |pages=48–53 |year=1996 |month=December |pmid=9216184 |doi= |url=