Salidroside

Salidroside

chembox new
ImageFile=Salidroside.pngImageSize=220px
IUPACName=(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6- [2-(4-hydroxyphenyl)ethoxy] oxane-3,4,5-triol
OtherNames=Salidroside, Rhodioloside
Section1=Chembox Identifiers
CASNo=10338-51-9
PubChem=159278
SMILES=C1=CC(=CC=C1CCO [C@H] 2 [C@@H] ( [C@H] ( [C@@H] ( [C@H] (O2)CO)O)O)O)O
MeSHName=

Section2=Chembox Properties
Formula=C14H20O7
MolarMass=300.304
Appearance=
Density=
MeltingPt=
BoilingPt=
Solubility=

Section3=Chembox Hazards
MainHazards=
FlashPt=
Autoignition=

Salidroside (Rhodioloside) is a glycoside compound found in the plant "Rhodiola rosea". It is thought to be one of the compounds responsible for the antidepressant and anxiolytic actions of this plant, along with rosavin. [Perfumi M, Mattioli L. Adaptogenic and central nervous system effects of single doses of 3% rosavin and 1% salidroside Rhodiola rosea L. extract in mice. "Phytotherapy Research". 2007 Jan;21(1):37-43. PMID 17072830] [Mattioli L, Funari C, Perfumi M. Effects of Rhodiola rosea L. extract on behavioural and physiological alterations induced by chronic mild stress in female rats. "Journal of Psychopharmacology. 2008 May 30. PMID 18515456] Salidroside may be more active than rosavin, [Panossian A, Nikoyan N, Ohanyan N, Hovhannisyan A, Abrahamyan H, Gabrielyan E, Wikman G. Comparative study of Rhodiola preparations on behavioral despair of rats. "Phytomedicine". 2008 Jan;15(1-2):84-91. PMID 18054474] even though many commercially marketed "Rhodiola rosea" extracts are standardised for rosavin content rather than salidroside.

References


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