Leonurine

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ImageFile=Leonurine structure.pngImageSize=200px
IUPACName=4-Hydroxy-3,5-dimethoxybenzoic acid 4-guanidinobutyl ester
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CASNo=24697-74-3
PubChem=161464
SMILES=COC1=CC(=CC(=C1O)OC)C(=O)OCCCCN=C(N)N
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Formula=C₁₄H₂₁N₃O₅
MolarMass=311.33 g/mol
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Leonurine is one of the chemical constituents of the South African plant "Leonotis leonurus". It is a psychoactive alkaloid found in species "Leonotis nepetifolia", "Leonotis artemisia" as well as other plants of family Lamiaceae. Leonurine is easily extracted into water, as well as from the effective component of Leonurus sibiricus [cite web|url=http://www.newstar-chem.com/english/display.asp?id=208|title=The Leonurine and its preparation|date=2008|publisher=An Hui New Star Pharmaceutical Development Co.|language=English|accessdate=2008-08-28] .

Traditional uses

Primary uses include treatment of:
*Respiratory tract infections caused by "Streptococcus pneumoniae" and group A β-hemolytic streptococci.
*Otitis media due to "S. pneumoniae", "Hemophilus influenzae", "Moraxella catarrhalis", staphylococci, streptococci, and "N. catarrhalis".
*GU infections (including acute prostatitis) due to "Escherichia coli", "Proteus mirabilis" or "Klebsiella" species.
*Bone infections caused by "P. mirabilis" or "staphylococci".
*Skin and skin structure infections due to "staphylococci" and "streptococci".

References

Further reading

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