Falecalcitriol

Drugbox
IUPAC_name = (1"R",3"S",5"Z")-5- [(2"E")-2- [(1"R",3a"S",7a"R")-7a-Methyl-1- [(2"R")-7,7,7-trifluoro-6-hydroxy-6-(trifluoromethyl)heptan-2-yl] -2,3,3a,5,6,7-hexahydro-1"H"-inden-4-ylidene] ethylidene] -4-methylidenecyclohexane-1,3-diol

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CAS_number = 83805-11-2
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PubChem = 5282190
DrugBank =
chemical_formula =
C=27 | H=38 | F=6 | O=3
molecular_weight = 524.57 g/mol
smiles = C [C@H] (CCCC(C(F)(F)F)(C(F)(F)F)O) [C@H] 1CC [C@@H] 2 [C@@] 1(CCC/C2=CC=C/3C [C@H] (C [C@@H] (C3=C)O)O)C
bioavailability =
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legal_status = Rx-only
routes_of_administration = Oral

Falecalcitriol (INN) is an analog of calcitriol. It has a higher potency both in vivo and in vitro systems, and longer duration of action in vivo.cite journal |author=Okamoto S, Ejima E, Kiriyama T, "et al" |title=Mechanism of action of newly developed vitamin D analogue |journal=Contrib Nephrol |volume=91 |issue= |pages=146–8 |year=1991 |pmid=1666031 |doi= |url=]

References