5-HT4 agonist

5-HT4 agonist

A 5-HT4 agonist is a type of serotonin receptor agonist which act preferentially at the 5-HT4 receptor.

An example is lubiprostone.cite journal |author=Thomas J |title=Cancer-related constipation |journal=Curr Oncol Rep |volume=9 |issue=4 |pages=278–84 |year=2007 |month=July |pmid=17588352 |doi= |url= |accessdate=2008-07-13]

Another example is tegaserod.cite journal |author=Seerden TC, De Man JG, Holzer P, "et al" |title=Experimental pancreatitis disturbs gastrointestinal and colonic motility in mice: effect of the prokinetic agent tegaserod |journal=Neurogastroenterol. Motil. |volume=19 |issue=10 |pages=856–64 |year=2007 |month=October |pmid=17883437 |doi=10.1111/j.1365-2982.2007.00968.x |url= |accessdate=2008-07-13] cite journal |author=Cole P, Rabasseda X |title=Tegaserod: a serotonin 5-HT4 receptor agonist for treatment of constipation-predominant irritable bowel syndrome |journal=Drugs Today |volume=40 |issue=12 |pages=1013–30 |year=2004 |month=December |pmid=15645012 |doi= |url=http://journals.prous.com/journals/servlet/xmlxsl/pk_journals.xml_summaryn_pr?p_JournalId=4&p_RefId=872576 |accessdate=2008-07-13]

References


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