Johann Joseph Scherer

Johann Joseph Scherer (March 18, 1814 - February 17, 1869) was a German physician and chemist who was born in Aschaffenburg.

In 1836 he graduated from the University of Würzburg, where he studied medicine, chemistry, geology and mineralogy. From 1836 to 1838 he practiced medicine in Wipfeld, and afterwards continued in studies in chemistry at the University of Munich. In 1840 he worked in the laboratory of Justus Liebig (1803-1873) at Giessen, and in 1842 returned to Würzburg as a professor of organic chemistry. During his career at Würzburg, he held the title of professor in the departments of general, inorganic, and pharmacological chemistry, and also attained the directorship of the Medical Institute for Chemistry and Hygiene.

Scherer was a pioneer of clinical chemistry, and is remembered for applying his knowledge of chemistry to problems in the field of medicine. He made contributions in the study of urine and blood in pathological conditions, and in 1843 and 1851 demonstrated the presence of lactic acid in human blood under conditions such as hemorrhagic and septic shock. Scherer is also credited with the discoveries of inositol and the purine derivative known as hypoxanthine.

Beginning in 1852, with Rudolf Virchow (1821-1902) and Gottfried Eisenmann (1795-1867) he was co-editor of Karl Friedrich Canstatt’s (1807-1850) annual reports, "Jahresbericht über die Leistungen und Fortschritte der gesammten Medicin". One of his better known publications was the 1843 book "Chemische und Mikroskopische Untersuchungen zur Pathologie angestellt an den Kliniken des Julius-Hospitales zu Würzburg" (Chemical and Microscopic Investigations of Pathology performed at the Julius Hospital Clinic at Würzburg).

References

* [http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2040486 The first demonstration of lactic acid in human blood in shock]
* [http://www.clinchem.org/cgi/content/full/49/10/1696 Clinical chemistry, Justus Liebig and Animal Chemistry]
* [http://clendening.kumc.edu/dc/rv/cv3.html Autobiographical Outline of Rudolf Virchow, Manuscipts]
* [http://books.google.com/books?id=na_heGaFNwsC&pg=PA288&lpg=PA288&dq=Scherer+hypoxanthine+inositol&source=web&ots=EvAh0YCYII&sig=a0eHn06PpZcXKq7B1HNo7nxU0wI&hl=en&sa=X&oi=book_result&resnum=4&ct=result Contrasts in Scientific Style: Research Groups in Chemistry, Biographical Information]