B59

B59 may refer to :
* Bundesstraße 59, a German road
* Volvo B59, a rear-engined bus chassis produced by Volvo in Sweden
* HLA-B59, an HLA-B serotype
* Sicilian, Boleslavsky variation, 7.Nb3, according to the list of chess openings
* Barnard 59, an alternate name for Pipe Nebula in astonomy

B-59 may refer to :
* Boeing XB-59, an American aircraft

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