CP 47,497

Drugbox
IUPAC_name = 2- [(1R,3S)-3-hydroxycyclohexyl] -5-(2-methyloctan-2-yl)phenol

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width= 240
CAS_number= 70434-82-1
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PubChem= 125835
DrugBank=
C=21 | H=34 | O=2
molecular_weight = 318.492 g/mol
smiles = Oc1cc(C(C)(C)CCCCCC)ccc1C(CCC2)CC2O
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CP 47,497 is a drug which is a cannabinoid receptor agonist, developed by Pfizer in the 1980s. It has analgesic effects and is used in scientific research. It is a potent CB₁ agonist with a Ki of 2.1nM. [Shim JY, Welsh WJ, Howlett AC. Homology model of the CB1 cannabinoid receptor: sites critical for nonclassical cannabinoid agonist interaction. "Biopolymers". 2003;71(2):169-89. PMID 12767117] [Roger Pertwee. Cannabinoids. Handbook of Experimental Pharmacology Volume 168. Springer. ISBN 3-540-22565-X] [Little PJ, Compton DR, Johnson MR, Melvin LS, Martin BR. Pharmacology and stereoselectivity of structurally novel cannabinoids in mice. "Journal of Pharmacology and Experimental Therapeutics" 1988; 247:1046–1051.]

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