UBP-302

UBP-302

Chembox new
ImageFile=UBP-302.pngImageSize=240px
IUPACName=(S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione
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Section1= Chembox Identifiers
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SMILES=O=C(O)c2ccccc2Cn1c(=O)n(CC(N)C(O)=O)ccc1=O
MeSHName=

Section2= Chembox Properties
Formula=C15H15N3O6
MolarMass=333.296 g/mol
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Section3= Chembox Hazards
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UBP-302 is a highly selective Kainate receptor antagonist used in the study of many neurological processes. It is active at micromolar concentration within an "in vitro" preparation and specifically targets the GluR5 subunit of the receptor. [More JC, Nistico R, Dolman NP, Clarke VR, Alt AJ, Ogden AM, Buelens FP, Troop HM, Kelland EE, Pilato F, Bleakman D, Bortolotto ZA, Collingridge GL, Jane DE. Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist. "Neuropharmacology". 2004 Jul;47(1):46-64. PMID 15165833] It has only been recently made commercially available through such companies as Tocris.

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