- NDST3
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N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 Identifiers Symbols NDST3; HSST3; MGC130028; MGC130029 External IDs OMIM: 603950 MGI: 1932544 HomoloGene: 3513 GeneCards: NDST3 Gene EC number 2.8.2.8 Gene Ontology Molecular function • sulfotransferase activity
• [heparan sulfate-glucosamine N-sulfotransferase activity]
• transferase activity
• hydrolase activityCellular component • Golgi membrane
• Golgi apparatus
• membrane
• integral to membraneBiological process • protein amino acid deacetylation
• protein amino acid sulfationSources: Amigo / QuickGO RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 9348 83398 Ensembl ENSG00000164100 ENSMUSG00000027977 UniProt O95803 Q14DQ0 RefSeq (mRNA) NM_004784 NM_031186.2 RefSeq (protein) NP_004775 NP_112463.2 Location (UCSC) Chr 4:
118.95 – 119.18 MbChr 3:
123.23 – 123.39 MbPubMed search [1] [2] Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 is an enzyme that in humans is encoded by the NDST3 gene.[1][2]
References
- ^ Aikawa J, Esko JD (Mar 1999). "Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family". J Biol Chem 274 (5): 2690–5. doi:10.1074/jbc.274.5.2690. PMID 9915799.
- ^ "Entrez Gene: NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9348.
Further reading
- Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=403697.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Aikawa J, Grobe K, Tsujimoto M, Esko JD (2001). "Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4.". J. Biol. Chem. 276 (8): 5876–82. doi:10.1074/jbc.M009606200. PMID 11087757.
- "Toward a complete human genome sequence.". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
- Boutry M, Vassarotti A, Ghislain M, et al. (1984). "Isolation of the structural genes for the alpha and beta subunits of the mitochondrial ATPase from the fission yeast Schizosaccharomyces pombe.". J. Biol. Chem. 259 (5): 2840–4. PMID 6230352.
Categories:- Human proteins
- Chromosome 4 gene stubs
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