BRUNOL4

Bruno-like 4, RNA binding protein (Drosophila), also known as BRUNOL4, is a human gene.cite web | title = Entrez Gene: BRUNOL4 bruno-like 4, RNA binding protein (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56853| accessdate = ]

PBB_Summary
section_title =
summary_text = Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Several transcript variants encoding different isoforms have been found for this gene, but their full-length nature has not been determined yet.cite web | title = Entrez Gene: BRUNOL4 bruno-like 4, RNA binding protein (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56853| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Szafranski K, Schindler S, Taudien S, "et al." |title=Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. |journal=Genome Biol. |volume=8 |issue= 8 |pages= R154 |year= 2008 |pmid= 17672918 |doi= 10.1186/gb-2007-8-8-r154
*cite journal | author=Han J, Cooper TA |title=Identification of CELF splicing activation and repression domains in vivo. |journal=Nucleic Acids Res. |volume=33 |issue= 9 |pages= 2769-80 |year= 2005 |pmid= 15894795 |doi= 10.1093/nar/gki561
*cite journal | author=Singh G, Charlet-B N, Han J, Cooper TA |title=ETR-3 and CELF4 protein domains required for RNA binding and splicing activity in vivo. |journal=Nucleic Acids Res. |volume=32 |issue= 3 |pages= 1232-41 |year= 2004 |pmid= 14973222 |doi= 10.1093/nar/gkh275
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Tchernev VT, Mansfield TA, Giot L, "et al." |title=The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins. |journal=Mol. Med. |volume=8 |issue= 1 |pages= 56-64 |year= 2002 |pmid= 11984006 |doi=
*cite journal | author=Ladd AN, Charlet N, Cooper TA |title=The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing. |journal=Mol. Cell. Biol. |volume=21 |issue= 4 |pages= 1285-96 |year= 2001 |pmid= 11158314 |doi= 10.1128/MCB.21.4.1285-1296.2001
*cite journal | author=Good PJ, Chen Q, Warner SJ, Herring DC |title=A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator. |journal=J. Biol. Chem. |volume=275 |issue= 37 |pages= 28583-92 |year= 2000 |pmid= 10893231 |doi= 10.1074/jbc.M003083200
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi=

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