NUDT5

NUDT5
Nudix (nucleoside diphosphate linked moiety X)-type motif 5

PDB rendering based on 2dsb.
Identifiers
Symbols NUDT5; YSA1; YSA1H; hYSAH1
External IDs OMIM609230 MGI1858232 HomoloGene5388 GeneCards: NUDT5 Gene
EC number 3.6.1.13
Orthologs
Species Human Mouse
Entrez 11164 53893
Ensembl ENSG00000165609 ENSMUSG00000025817
UniProt Q9UKK9 Q9JKX6
RefSeq (mRNA) NM_014142 NM_016918.3
RefSeq (protein) NP_054861 NP_058614.1
Location (UCSC) Chr 10:
12.21 – 12.24 Mb
Chr 2:
5.77 – 5.79 Mb
PubMed search [1] [2]

ADP-sugar pyrophosphatase is an enzyme that in humans is encoded by the NUDT5 gene.[1][2]

Nudix hydrolases, such as NUDT5, eliminate toxic nucleotide derivatives from the cell and regulate the levels of important signaling nucleotides and their metabolites (McLennan, 1999).[supplied by OMIM][2]

References

  1. ^ McLennan AG (Aug 1999). "The MutT motif family of nucleotide phosphohydrolases in man and human pathogens (review)". Int J Mol Med 4 (1): 79–89. PMID 10373642. 
  2. ^ a b "Entrez Gene: NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11164. 

Further reading


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”