Gastão Rosenfeld

Gastão Rosenfeld (b. Budapest, July 26 1912; d. São Paulo, July 15 1990), was a Brazilian physician and biomedical scientist, one of the co-discoverers of bradykinin, together with Maurício Rocha e Silva and Wilson Teixeira Beraldo, in 1949.

Rosenfeld was a specialist in the study of biochemistry of the action of snake venoms in animals and humans, particularly those of the Bothrops family (lancehead or jararaca). Among other things, he investigated in the Instituto Butantan, in São Paulo, where he worked as an experimental researcher, the action of snake venoms on fibrinolysis and blood coagulation.Among his contributions to biomedical sciences are the development of a rapid staining for blood smears combining May-Grunwald and Giemsa techniques in 1947 (Rosenfeld staining), introduced a new treatment for chronic leukemia using personal control of maintenance dosis (1955) and described hementerin, an anticoagulant isolated of a Brazilian specie of leech ("Haementeria depressa") jointly with Eva Maria Antonia Kelen in 1975. Dr. Rosenfeld was also an important scientific leader, having been involved in the foundation of the Brazilian Society for the Advancement of Science, in 1949.

May-Grunwald-Giemsa blood staining technique [http://www.geocities.com/csstoica/movies.html video]

Bibliography

Kelen EM, Rosenfeld G, Vainzof M, Machado ZC. Experimental defibrination and bothropase: a study on the fibrinolytic mechanism in vivo. "Haemostasis". 1978;7(1):35-45.

Kelen, EM- Gastão Rosenfeld (26/07/1912-15/07/1990). "Ciência e Cultura" 42(12)Dec.1990