Pleuran

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CASNo = 159940-37-1
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MolarMass = 762 kD
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Pleuran is an insoluble polysaccharide (β-(1,3/1,6)-D-glucan), isolated from "Pleurotus ostreatus". [cite journal | coauthors = Karácsonyi S, Kuniak L | year = 1994 | title = Polysaccharides of "Pleurotus ostreatus": Isolation and structure of pleuran, an alkali-insoluble β-glucan | journal = Carbohydrate Polymers | volume = 24 | issue = 2 | pages = 107-111 | publisher = Elsevier | location = | issn = 0144-8617 | doi = 10.1016/0144-8617(94)90019-1 ]

Pleuran belongs to a group of glucose polymers commonly called beta-glucans demonstrating biological response modifier properties. These immunomodulating properties render the host more resistant to infections and neoplasms. [cite journal | last = Di Luzio | first = NR | year = 1985 | title = Update on the immunomodulating activities of glucans | journal = Springer seminars in immunopathology | volume = 8 | issue = 4 | pages = 387-400 | publisher = Springer Verlag | location = Germany | issn = 0344-4325 | pmid = 4089757 ]

Pleuran is also being studied as a potential immunologic adjuvant (Mojžišová et al. 2005). [cite paper | coauthors = Vogel FR, Powell MF, Alving CR | title = A Compendium of Vaccine Adjuvants and Excipients | version = 2nd ed | pages = p. 77 | publisher = National Institute of Allergy and Infectious Diseases | date = 1998 | url = http://www.niaid.nih.gov/hivvaccines/pdf/compendium.pdf | accessdate = 2008-05-08]

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