Avimer proteins

Avimer proteins

Avimer Proteins are multimeric binding proteins or peptides engineered using in vitro exon shuffling and phage display. Multiple binding domains are linked, resulting in greater affinity and specificity compared to single epitope immunoglobin domains. [ [http://www.nature.com/nbt/journal/v23/n12/abs/nbt1166.html Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains - Nature Biotechnology ] ] These properties make avimer proteins extremely useful as potential tools and therapeutics.

References

Expert Opinion on Investigational DrugsJune 2007, Vol. 16, No. 6, Pages 909-917


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