WNT5B

Wingless-type MMTV integration site family, member 5B, also known as WNT5B, is a human gene.

PBB_Summary
section_title =
summary_text = The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants.cite web | title = Entrez Gene: WNT5B wingless-type MMTV integration site family, member 5B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81029| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Smolich BD, McMahon JA, McMahon AP, Papkoff J |title=Wnt family proteins are secreted and associated with the cell surface. |journal=Mol. Biol. Cell |volume=4 |issue= 12 |pages= 1267–75 |year= 1994 |pmid= 8167409 |doi=
*cite journal | author=Tanaka K, Okabayashi K, Asashima M, "et al." |title=The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. |journal=Eur. J. Biochem. |volume=267 |issue= 13 |pages= 4300–11 |year= 2000 |pmid= 10866835 |doi=10.1046/j.1432-1033.2000.01478.x
*cite journal | author=Saitoh T, Katoh M |title=Molecular cloning and characterization of human WNT5B on chromosome 12p13.3 region. |journal=Int. J. Oncol. |volume=19 |issue= 2 |pages= 347–51 |year= 2001 |pmid= 11445850 |doi=
*cite journal | author=Saitoh T, Katoh M |title=Expression and regulation of WNT5A and WNT5B in human cancer: up-regulation of WNT5A by TNFalpha in MKN45 cells and up-regulation of WNT5B by beta-estradiol in MCF-7 cells. |journal=Int. J. Mol. Med. |volume=10 |issue= 3 |pages= 345–9 |year= 2003 |pmid= 12165812 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Kanazawa A, Tsukada S, Sekine A, "et al." |title=Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes. |journal=Am. J. Hum. Genet. |volume=75 |issue= 5 |pages= 832–43 |year= 2005 |pmid= 15386214 |doi= 10.1086/425340
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Mangioni S, Viganò P, Lattuada D, "et al." |title=Overexpression of the Wnt5b gene in leiomyoma cells: implications for a role of the Wnt signaling pathway in the uterine benign tumor. |journal=J. Clin. Endocrinol. Metab. |volume=90 |issue= 9 |pages= 5349–55 |year= 2005 |pmid= 15972578 |doi= 10.1210/jc.2005-0272
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

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