SLC2A9

SLC2A9

Solute carrier family 2 (facilitated glucose transporter), member 9, also known as SLC2A9, is a human gene.cite web | title = Entrez Gene: SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56606| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene.cite web | title = Entrez Gene: SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56606| accessdate = ]

SLC2A9 has also recently been found to transport uric acid and genetic variants of the transporter have been linked to increased risk of development of gout.cite journal | author = Vitart V, Rudan I, Hayward C, "et al" | title = SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout | journal = Nature Genetics | volume = 40 | issue = 4 | pages = | year = 2008 | pmid = | doi = 10.1038/ng.106 | issn = ] cite journal | author = Döring A, Gieger C, Mehta D, "et al" | title = SLC2A9 influences uric acid concentrations with pronounced sex-specific effects | journal = Nature Genetics | volume = 40 | issue = 4 | pages = | year = 2008 | pmid = | doi = 10.1038/ng.107 | issn = ]

ee also

* Glucose transporter
* Solute carrier family

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Phay JE, Hussain HB, Moley JF |title=Cloning and expression analysis of a novel member of the facilitative glucose transporter family, SLC2A9 (GLUT9). |journal=Genomics |volume=66 |issue= 2 |pages= 217–20 |year= 2000 |pmid= 10860667 |doi= 10.1006/geno.2000.6195
*cite journal | author=Doege H, Bocianski A, Joost HG, Schürmann A |title=Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes. |journal=Biochem. J. |volume=350 Pt 3 |issue= |pages= 771–6 |year= 2001 |pmid= 10970791 |doi=
*cite journal | author=Shikhman AR, Brinson DC, Valbracht J, Lotz MK |title=Cytokine regulation of facilitated glucose transport in human articular chondrocytes. |journal=J. Immunol. |volume=167 |issue= 12 |pages= 7001–8 |year= 2001 |pmid= 11739520 |doi=
*cite journal | author=Mobasheri A, Neama G, Bell S, "et al." |title=Human articular chondrocytes express three facilitative glucose transporter isoforms: GLUT1, GLUT3 and GLUT9. |journal=Cell Biol. Int. |volume=26 |issue= 3 |pages= 297–300 |year= 2002 |pmid= 11991658 |doi= 10.1006/cbir.2001.0850
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Richardson S, Neama G, Phillips T, "et al." |title=Molecular characterization and partial cDNA cloning of facilitative glucose transporters expressed in human articular chondrocytes; stimulation of 2-deoxyglucose uptake by IGF-I and elevated MMP-2 secretion by glucose deprivation. |journal=Osteoarthr. Cartil. |volume=11 |issue= 2 |pages= 92–101 |year= 2003 |pmid= 12554125 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Augustin R, Carayannopoulos MO, Dowd LO, "et al." |title=Identification and characterization of human glucose transporter-like protein-9 (GLUT9): alternative splicing alters trafficking. |journal=J. Biol. Chem. |volume=279 |issue= 16 |pages= 16229–36 |year= 2004 |pmid= 14739288 |doi= 10.1074/jbc.M312226200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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