SIRT7

Sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae), also known as SIRT7, is a human gene.cite web | title = Entrez Gene: SIRT7 sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51547| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.cite web | title = Entrez Gene: SIRT7 sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51547| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Frye RA |title=Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. |journal=Biochem. Biophys. Res. Commun. |volume=273 |issue= 2 |pages= 793–8 |year= 2000 |pmid= 10873683 |doi= 10.1006/bbrc.2000.3000
*cite journal | author=de Nigris F, Cerutti J, Morelli C, "et al." |title=Isolation of a SIR-like gene, SIR-T8, that is overexpressed in thyroid carcinoma cell lines and tissues. |journal=Br. J. Cancer |volume=86 |issue= 6 |pages= 917–23 |year= 2002 |pmid= 11953824 |doi= 10.1038/sj.bjc.6600156
*cite journal | author=De Nigris F, Cerutti J, Morelli C, "et al." |title=Isolation of a SIR-like gene, SIR-T8, that is overexpressed in thyroid carcinoma cell lines and tissues. |journal=Br. J. Cancer |volume=87 |issue= 12 |pages= 1479 |year= 2003 |pmid= 12454780 |doi= 10.1038/sj.bjc.6600636
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Voelter-Mahlknecht S, Letzel S, Mahlknecht U |title=Fluorescence in situ hybridization and chromosomal organization of the human Sirtuin 7 gene. |journal=Int. J. Oncol. |volume=28 |issue= 4 |pages= 899–908 |year= 2006 |pmid= 16525639 |doi=
*cite journal | author=Ford E, Voit R, Liszt G, "et al." |title=Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription. |journal=Genes Dev. |volume=20 |issue= 9 |pages= 1075–80 |year= 2006 |pmid= 16618798 |doi= 10.1101/gad.1399706
*cite journal | author=Ashraf N, Zino S, Macintyre A, "et al." |title=Altered sirtuin expression is associated with node-positive breast cancer. |journal=Br. J. Cancer |volume=95 |issue= 8 |pages= 1056–61 |year= 2006 |pmid= 17003781 |doi= 10.1038/sj.bjc.6603384

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes